Released under the GIC Framework
Innovative thinker, Jenine Alexander built a mobile home, made purely from materials she found around her. "It's a house that's mobile… For me it just made sense because I don't own any land yet. Land is so expensive around here like I don't have access to that kind of opportunity. What do I have access to, the dump, to craigslist."
With help from tiny house blogs and a DIY book from the 1950s, Jenine was able to create a home for less than $3,500. Jenine recorded her day-by-day progress on her tiny house project and shared it through her own personal blog which in turn gained a great following. This inturn, motivated her, with the help from others, to build and sell another home just like hers!
How could we take the Global Innovation Commons and apply it to this tiny house project? Read through, and figure it out!
The Kingdom of Saudi Arabia is facing a difficult problem. Apart from breast and cervical cancer, colorectal cancer is slowly taking its toll towards the younger generation in (the Kingdom of) Saudi Arabia. Being the third most common cancer in the world, this disease is affecting the * .
"Colorectal Cancer (CRC), Colon Cancer and Cancer of the Rectum usually begin as a small polyp. While most colon polyps are benign, some do become cancerous. Colon cancer symptoms may include a change in bowel habits or bleeding, but usually colon cancer strikes without symptoms. That’s why it’s important to get a colon cancer screening test, such as a colonoscopy. If the cancer is found early, the doctor can use surgery, radiation, and/or chemotherapy for effective treatment.**"
In this set of Global Innovation Commons open source technologies, solutions to CRC Surgery, Antibody Compositions, Bioinformatics, Molecular Biology, Drug - Gene Therapy, and Organic Compounds - Peptides are provided.
Click to view the Global Innovation Commons Sets on Colorectal Cancer HERE
We at the Global Innovation Commons are please to welcome our highly regarded friend, Dr. Mohammad Azhar Aziz, as a guest collaborator on this initiative. Dr. Aziz intends to establish a Center for Familial Colorectal Cancer at the King Abdullah International Medical Research Center National Guard Health Affairs in Riyadh, Kingdom Saudi Arabia. The aim of the Center is to create scientific awareness for hereditary colorectal cancer in the Kingdom of Saudi Arabia. The proposal follows below:
Proposal for the Development of a Center for Familial Colorectal Cancer to create scientific awareness for hereditary colorectal cancer counselling, genetic diagnostics, surveillance and treatment in the Kingdom of Saudi Arabia
A better understanding of the molecular basis of hereditary colorectal cancer syndromes yields profound consequences for the diagnosis, surveillance and prophylactic treatment of (pre)malignant neoplastic lesions. Sequence analysis of the underlying genes for these tumours and the detection of disease-causing genetic alterations in a proband enable predictive testing for individuals at risk within an affected family.
The Dresden Center for Familial Colorectal Cancer has been since 1995 active in the study of the molecular basis of several Colorectal Cancer Syndromes. Together with human geneticists and clinicians, we, the members of the Department of Surgical Research, have screened 1316 patients with hereditary tumours and performed molecular diagnostics for various syndromes such as Peutz-Jeghers Syndrome (Gene: STK11), Cowden Syndrome (PTEN), and Familial Adenomatous Polyposis coli (APC, MUTYH). The most frequent cause of familial colorectal cancer remains HNPCC or Lynch Syndrome caused by mutations of Mismatch Repair (MMR) Genes MSH2, MLH1, MSH6 andPMS2. We have identified germline mutations in 224 families and have performed predictive diagnostics in 296 relatives of probands. A HNPCC specific surveillance is highly recommended for probands who are carriers of MMR-deficient tumors or mutation carriers and their relatives. Our prospective data on the efficacy of colonoscopic surveillance in individuals with HNPCC suggest that annual colonoscopic surveillance is recommended for individuals with HNPCC.
In addition, we have contributed five families to worldwide reports of more than 70 families with biallelic mutations in MMR genes. Most of those patients are the offspring of a consanguineous marriage. Tumor spectrum of patients with biallelic germline mutations is different from HNPCC.
The necessity for proper assessment of the risk of familial colorectal cancer has become increasingly evident. In Germany alone, this inherited condition remains largely unrecognized in up to 3,000 colorectal cancer patients per year, while the benefit of surveillance and screening in at risk patients and families has been clearly documented. Further recommendations based on predictive molecular testing such as prophylactic treatment, require critical evidence-based evaluation.
Based on the experience of the Dresden Center for Familial Colorectal Cancer, we intend to establish a Center for Familial Colorectal Cancer at the King Abdullah International Medical Research Center National Guard Health Affairs in Riyadh, Kingdom Saudi Arabia. Our aim is to create scientific awareness for hereditary colorectal cancer in the Kingdom of Saudi Arabia.
The objective of the proposed mission is to establish a Center for Familial Colorectal Cancer at the King Abdullah International Medical Research Center National Guard Health Affairs in Riyadh, Kingdom of Saudi Arabia. We aim at creating scientific awareness for hereditary colorectal cancer prescreening in the Kingdom of Saudi Arabia.
This mission will be accomplished in close cooperation between the Center for Familial Colorectal Dresden at the University of Dresden, Germany (Prof. Dr. med. Hans K. Schackert, Chief Executiveof the Center for Familial Colorectal Cancer Dresden) and the King Abdullah International Medical Research Center National Guard Health Affairs in Riyadh, Kingdom of Saudi Arabia (Dr. Mohammad Azhar Aziz, PhD, Associate Research Scientist).
The German organization GTZ provides this proposal.
This page will contain updates on the initiative as it progresses.
This innovative car wash located in Curacao, a Dutch Caribbean island, has the ability to adjust the intensity of the water, as well as the amount of chemicals and energy used during each car wash based on the dirtiness of the car. This car wash, unlike most, will no longer treat each car the same and allows for a environmental friendly solution to the average car wash.
Sustainable Cities International, or SCI, is a partnership between three different levels of organizations, government, private sector and civil society, was founded in Canada in 1993 with the idea to "catalyze action on urban sustainability in cities around the world." SCI focuses on creating sustainable cities using "co-creating urban sustainability" based on three major purpose: Sustainability + Design Thinking + Stakeholder Engagement. Through these three purposes, SCI has been able to facilitate an international network of sustainable cities that are used as urban laboratories which adopt, test and improve on innovations.
A sustainable city, or eco-city, is designed with consideration of environmental impact in mind and strives to development a urban infrastructure. With 82% of the American population living in cities, and an expected 90% to live in cities by 2050, sustainable cities would allow people to use less resources in their urban areas. 75% of energy used, 60% of water used, and 80% of greenhouse gases produced in America come from cities, but with the idea of sustainable cities, these number would significantly decrease.
Through multiple projects, SCI works with developing cities in countries such as South Africa, China, Sri Lanka, Brazil, and Mexico. SCI works to connect and mobilize people around technological and social innovations, thriving for urban sustainability.
How could we take the technology in the Global Innovation Commons and apply them to the Sustainable Cities project? Lets dive in and find out!
To read more about what Sustainable Cities International is doing, click here
A robot that can create itself, University of Pennsylvania's Foambot is our Wacky Technology Wednesday highlight this week. This innovative robot that builds itself out of foam, constructing itself on the spot depending on what type of robot you need. Based on a "mothership" platform, the Foambot's mothership configures joints on the ground using a foaming spray, a mixture of chemical reagents, that hardens and expands. These "joints" are coordinated by a piece of software that is then analyzed by the mothership and creates a "motion scheme." Although the technology of the Foambot is in its early stages, its interesting to see what innovative thinking can do, and its not hard to envision the potential this make-as-you-go platform will eventually be able to do.
To read the full article about the Foambot click here
Just one of the amazing things water can do! What other things can we use water for in places where it is in abundance?
"Jetlev Flyer is an innovative personal flying machine that employs a powerful 215 HP engine and water nozzle reaction force to achieve stable and controlled flight. http://www.jetlev-flyer.com/
The Million Tree Project is a Shangai Roots & Shoots initiative that is working together to plant one million trees in Mongolia to stop desertifcation and help offset China's greenhouse emissions. A project that began in 2007, The Million Tree Project, or MTP, aims to plant one million trees in the desert of Mongolia by 2014. A project launched by Shangai Roots & Shoots, MTP was developed to raise community awareness on the impact humans have on the earth and what individuals can do to counteract their negative impact.